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Athens to Rome with Regent Seven Seas Prestige

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Sail from Athens to Rome, discovering sun-soaked islands, ancient ruins and the spectacular Italian coastline, all in effortless luxury with Regent Seven Seas.
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EXCLUSIVE to Flat Beds Tour + Cruise – Receive US$550 onboard credit per couple.* 

Discover the stunning Mediterranean on the new Regent Seven Seas Prestige.

Experience the timeless beauty of the Mediterranean on a captivating seven-night journey from Athens to Rome, where ancient history, idyllic islands and spectacular coastlines come together. Begin in Athens before sailing to the sun-drenched shores of Mykonos and the ancient wonders of Ephesus, then discover the unspoiled charm of Milos. As you cruise through the Ionian Sea, the journey continues to Sicily, with a day in Messina offering a taste of the island’s rich culture, history and cuisine.

The final days bring you to the enchanting shores of Sorrento and the legendary island of Capri, before concluding in Rome, one of Europe’s most iconic cities. With a wonderful balance of celebrated destinations and beautiful lesser-known ports, this itinerary offers an enticing introduction to Greece, Turkey and Italy — filled with opportunities to explore ancient treasures, savour local flavours and soak up the unmistakable beauty of the Mediterranean.

Milos

What's Included

  • Unlimited Shore Excursions
  • Unlimited Beverages, Including Fine Wines and Spirits, Craft Cocktails, Specialty Coffees
  • Exquisite Dining, including Speciality Restaurants at no extra cost
  • Customised In-Suite Mini-Bar Replenished Daily
  • Unlimited Access to Spa Facilities
  • Pre-Paid Gratuities
  • Included 24-Hour In-Suite Dining
  • Included & Unlimited WiFi
  • Included Valet Laundry Service
  • CONCIERGE SUITES AND HIGHER INCLUDE: Included 1-Night Pre-Cruise Hotel Package* and more
  • PENTHOUSE SUITES AND HIGHER INCLUDE: Included Personal Butler and more

Map

Your Journey

Cruise Itinerary

DAY 1 - ATHENS (PIRAEUS), GREECE

Piraeus is the gateway to the ancient city of Athens, known as the “Cradle of Western Civilization” because of its immense impact on cultural and political achievements throughout the world. Due mainly to tourism and the 2004 Olympics, Greece has redeveloped many sites in Athens. A historian’s delight, Athens is home to such magnificent wonders as: the Acropolis, the Parthenon, the atmospheric winding streets of the Plaka, Temple of Olympian Zeus and Temple of Athena Nike, and the Archaeological Museum with the world’s finest collection of ancient artifacts.

Departure Time: 5pm

DAY 2 - MYKONOS, GREECE

Steeped in Greek mythological history, Mykonos was named after Apollo’s grandson, Mykons, and was the location of the grand battle between Zeus and the Gigantes. Today, this island is one of Greece’s most adored destinations due to its picture- postcard setting and growing nightlife. Mykonos is a superb example of Cycladic architecture, and by law even new buildings have to be built in the same style of whitewashed, organic, cube-like buildings. Be sure to plan a day trip to take in picturesque Little Venice, the unique Paraportiani church, and the archeological dig at Delos.

Arrival Time: 8am // Departure time: 6pm

DAY 3 - EPHESUS (KUSADASI), TURKEY

Europe’s classical metropolis, Ephesus, was one of the largest cities in all of the Roman Empire, boasting one of the Seven Wonders of the Ancient World, the Temple of Artemis. Explore the ruins of its massive Theater, the Temple of Hadrian and the magnificent Celsus Library.

Arrival Time: 8am // Departure time: 6pm

Unsplash WClG5w6GC9I Ephesus

DAY 4 - MILOS, GREECE

With over 70 beaches painted red, pink and orange reflecting off turquoise seas, Milos may be the most colorful of the famed Greek Isles. Stunning Sarakiniko resembles a lunar landscape of white limestone molded by wind and water, while Kleftiko boasts awe-inspiring arches and sea caves. In the white-washed capital village of Plaka, visit a museum housing a replica of the Venus de Milo statue, which was discovered on Milos in 1820. Head to the fishing village of Pollonia to sample wines and cheeses aged in cool, volcanically formed caverns.

Arrival Time: 8am // Departure time: 6pm

DAY 5 - CRUISING THE IONEAN SEA

DAY 6 - MESSINA (SICILY), ITALY

Messina, the third largest city in Sicily, was the most important port of departure for European knights on their way to the Crusades in the Middle Ages. Today, this extensively rebuilt port city still boasts many historically and architecturally significant landmarks, particularly the renowned cathedral with its unusual astronomical clock, the 12th century Catania Church and the ornate Teatro Vittorio Emanuele. Messina is also the starting point for a day trip to the peak of breath-taking Mt. Etna-Crateri Silvestri.

Arrival Time: 8am // Departure time: 5pm

DAY 7 - SORRENTO / CAPRI, ITALY

Sorrento is surely one of the world’s most beautiful towns, built on a coast with breathtaking views and landscapes. Yet it is far from a frivolous vacation destination. The houses, people and the entire region are filled with a history and culture so deep that it can be traced back to the 11th century BC. Overlooking the bay of Naples, the town is the key point on the Sorrentine Peninsula and is one of the most popular destinations of the entire Campania region. Make sure to plan a day trip to Capri, one of the most celebrated Italian islands, noted for its natural beauty.

Arrival Time: 8am // Departure time: 6pm

Rugged cliffs of a Mediterranean coast with white villas on the hillside and rock stacks rising from the sea.

DAY 8 - ROME, ITALY

Whether enjoying the street performers at the Spanish Steps and people-watching over a fine glass of wine in colorful Trastevere, or taking in the historical and architectural glory that is Rome, visitors are spoiled for choice in this truly Eternal City. St. Peter’s Basilica is a full-day outing, featuring the Sistine Chapel and panoramic city vistas for those willing to climb to the top of the dome. Other landmarks not to miss include the renowned Trevi Fountain, the Coliseum, and Aventine Hill, which provides you with a grand view of the imposing remains of the Imperial Palaces and the Circus Maximus, of Ben Hur fame.

Arrival Time: 7am

Regent Seven Seas Prestige

Seven Seas Prestige™ embodies the heart of the vision for the future of ocean travel. She furthers the Regent commitment to excellence as reflected in every aspect of her elevated design. Join Regent Seven Sease Cruises on a new journey toward sophistication and refinement that is the epitome of timeless elegance.

Be among the first to sail aboard this newest ship. Choose your preferred suite on an inaugural season voyage today.

Luxurious hotel lobby with a white spiral staircase, glass railings, and blue upholstered chairs.

THE SKY IS UNLIMITED ABOARD SEVEN SEAS PRESTIGE™

Skyview Suites

Introducing the Skyview Suites, one of twelve accommodation categories and available in three distinct layouts: Aura, Luna and Sola. These bespoke suites feature private in-suite elevators, second floor private terraces, the bespoke service of a personal butler, and so much more. Which will you choose?

Grand Loft Suite

With its contemporary design, this two-story, 856-square-foot suite evokes the feel of a refined Lower Manhattan residence. A soaring double-height space and extraordinary window wall create jaw-dropping views from the upstairs bed, which faces directly toward the horizon.

Horizon Penthouse Suite

Featuring a beautifully appointed bedroom, spacious living area plus an oversized 182-263-square-foot balcony with outdoor dining, a plush sofa and sun loungers. These limited 15 suites allow the opportunity to enjoy a seamless blend of indoor elegance and open-air relaxation.

Signature Suites

Offering a total of 2,037 sq. ft. the Signature Suites are outfitted with a rich color palette and the finest fabrics across two spacious bedrooms and two bathrooms, along with a generous living room. A private wraparound balcony — one of the largest at sea at 1,023 sq. ft. — extends the living space outdoors, making it ideal for entertaining or simply soaking in the view.

Grand Suites

The Grand Suites feature clean lines, mid-century inspired furniture and a color palette that features neutrals with shades of green. The design highlights Italian artistry with textured fabrics and woven leather accents, creating a sophisticated and luxurious ambiance. At 1,214-1,417 sq. ft., the suite houses a private terrace as well as a dining room for in-suite meals.

Bright open-concept living and dining area with large windows showing an ocean view, beige sofa, and modern decor.

Prestige Suites

At 813-1,354 sq. ft., the thoughtfully designed Prestige Suites are the embodiment of refined living at sea. The one-bedroom, one-and-a-half bathroom suites are designed with calming hues of cream, gray and brown. They feature a dining table for in-suite service, a spacious closet and an elegant bath.

Seven Seas Suites

Providing 721 sq. ft. of luxury, the Seven Seas Suites have been designed with a soothing color palette complemented by plush furnishings. The suite flows effortlessly from the living room to the dining area to the bedroom, with sliding glass doorways leading to a spacious private balcony. A magnificent bathroom sits adjacent to the oversized bedroom and large walk-in closet.

Penthouse Suites

This luxurious suite has been carefully designed to maximize space and comfort, with more than 600 square feet from door to balcony deck. As you make your way through the separated living and bedroom, you have the choice to section off the area with a pocket door for added privacy. Your Penthouse also features a spacious walk-through closet that offers ample storage.

Elegant open-air lounge on a balcony with white furniture and wicker chairs overlooking the ocean horizon.

Concierge Suites

Ranging from 440 to 485 sq. ft. the Concierge Suites aboard Seven Seas Prestige offer a sophisticated retreat complete with double vanities and a spacious, furnished veranda. Guests also enjoy the added benefits of priority online dining and shore excursion reservations, plus a one-night pre-cruise hotel package.

Serenity Suites

At 440 sq. ft., the Serenity Suites feature bluish teal accents, built-in minibars and screening elements that separate the bedroom and living area. Clean lines and contemporary detailing create a relaxing and inviting atmosphere.

Luxurious cruise cabin with a king bed, seating area, and round table set for two with champagne glasses; TV screen shows Regent Seven Seas Cruises.

Deluxe Veranda Suites

The Deluxe Veranda Suites aboard Seven Seas Prestige offer 440 sq. ft. of refined comfort. Each features a private balcony and a European King-Sized Elite Slumber® Bed.

Hotel room with two double beds, blue-gray accents, wall lamps, and a window with an ocean view.

SOCIAL SPACES

At the heart of the ship, twin spiral staircases gleaming in gold rise all the way to Deck 11.

Galileo's Bar

With views of the Grand Staircase, this is the perfect place to begin your evening.

Prestige Lounge

Inspired performances that will lure you to the dance floor as you sail across the ocean.

Meridian Lounge

An elegant and refined space that pays homage to the allure of uncovering new worlds.

Luxurious lounge with curved seating, blue chairs, and large windows overlooking the ocean.

Constellation Theatre

Designed with precision for you to enjoy every phenomenal performance.

DINING

Azure

New to the restaurant collection, a tribute to Mediterranean cuisine.

Compass Rose

This award-winning restaurant embodies the spirit of exploration and the serenity of the ocean.

Luxurious restaurant dining hall with round crystal chandeliers, marble columns, and sea view through windows.

Sette Mari at La Veranda

Delicious à la carte dinner menu of authentic Italian specialties and fine wines.

Prime 7

Drawing deep inspiration from Chicago’s storied past and the grandeur of its art deco skyline.

Luxurious hotel bar featuring a marble-front counter, brown wood panels, and upholstered bar stools lined up along the counter.

Chartreuse

A contemporary sanctuary for refined hospitality — where heritage and modernity converge.

Pacific Rim

Breathtaking views combine with mouthwatering Asian dishes in a Zen-like oasis.

La Veranda

Chic indoor dining and the most expansive al fresco area ever seen on a Regent ship.

Ship dining room with wood-panelled walls, rows of tables and sea views through the windows.

Day time Enrichment

You’ll find time spent on board the ship to be just as enriching as time ashore. Relax by the pool, compete in a friendly game of trivia or bocce ball, indulge in treats at afternoon tea and gain insight from an expert lecturer.

Evening Entertainment

Evenings on board are filled with music and fun. Enjoy a rousing cabaret show, test your luck at the Casino, step onto the stage for karaoke or simply find a quiet place on deck to revel in the symphony of stars.

Serene Spa and Wellness

Luxury travel is a holistic experience, one that reenergizes and restores the mind, body and spirit, leaving you with a greater sense of satisfaction and wellbeing. Serene Spa & Wellness™ invites you into a globally inspired, tranquil haven of health, beauty and wellness.

Spacious spa or gym on a ship with wooden walls, yoga mats, and neatly stacked towels by shelves overlooking the sea.

Booking Terms & Conditions

Advertised price based on 5 August 2027 departure in a Deluxe Verandah Suite GTY and includes any savings on offer. Pricing is correct as of 2 November 2026 and is subject to availability at the time of booking. Offers may be withdrawn or prices updated by the supplier at any time, so please enquire with our expert Flat Beds Tour + Cruise consultants for the latest pricing, terms and conditions. Solo supplement may apply for single travelers. *35th Anniversary Offer: US$350 onboard credit applies when booking applicable voyages. *Exclusive offer: Additional USD$200 per couple onboard credit apply when booking with Flat Beds Tour + Cruise.
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From

$9823

per person twin share
Duration
7 Nights
Destination
Europe, Mediterranean
Deal Type
Luxury Cruises, Ocean Cruise
Departures
2027/28 Sailings
From

$9823

per person twin share
Duration
7 Nights
Destination
Format
Travel Tier
Sailings
2027/28 Sailings

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DAY 7 - SOUDA BAY (CRETE), GREECE: The spectacular Souda Bay on the island of Crete is a perfect place to spend some time. Souda Bay is known for its charming ambience and incredible beaches, as well as for its medieval monuments such as the Frangokastello fortress. Visit picturesque Agii Apostoli beach or the lively Nea Chora beach to enjoy the sea.
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DAY 4 - SIRACUSA, ITALY: Siracusa or Syracuse, Sicily, Italy is has a plethora of winding alleys, gracious piazzas and glorious architecture represent a timeline of several millennia. Founded in 734 BC by the Greeks, the city was a major influencer in the spread of Judaism and Christianity and brims with world-class examples of Greek, Roman and Baroque architecture awash with Italian character. The entire city of Siracusa is a UNESCO World Heritage Site.
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DAY 3 - SALERNO, ITALY: There's far more to this lively port city than its location as a gateway to the Amalfi Coast. The Centro Storico – one of the region's best-preserved medieval centers – is an atmospheric maze of cobbled streets and alleys, dotted with trattorias offering authentic Neapolitan cuisine to a mostly local clientele. The city's Duomo has breathtakingly ornate interiors, rich with intricate mosaics and vivid frescos, while up above the city, the 6th-century Castello di Arechi offers spectacular views across the rooftops to the Gulf beyond. Quite why Salerno remains under the radar is a mystery.
DAY 6 - ZAKYNTHOS, GREECE: Known as the `Flower of the Levant,` Zakynthos offers breathtaking natural beauty. Often referred to as Zante, the Greek island situated in the Ionian Sea, off the western coast of mainland Greece, and is part of the Ionian Islands group, which are world renown for their stunning natural beauty, with turquoise waters, scenic beaches, and a lush interior landscape. The island's famous beach Navagio, with its iconic shipwreck and turquoise waters, is a must-visit, as are the enchanting Blue Caves, where you can immerse yourself (quite literally) in the island's maritime beauty with snorkeling and diving adventures. Wander through Zakynthos Town's charming streets, stopping off at Solomos Square, named after Greece's national poet Dionysios Solomos, and the Byzantine Museum to explore the island's artistic and historical treasures. When you've worked up a sufficient hunger, find a table at a taverna to try savory Greek cuisine such as moussaka and souvlaki. Don't miss out on local specialties like `skordostoumbi,` a garlic-infused pasta dish, or `bourekia,` delectable pastries filled with cheese or meat, and `ladotyri,` a unique cheese matured in olive oil. Local wines such as Verdea and Avgoustiatis, perfect for wine enthusiasts.
ACCOMMODATION & SUITES: The guest rooms and suites are havens of comfort and calm, inviting you to relax and let Crystal take care of your every need. Every guest room and suite enjoys 24-hour private butler service, giving you the convenience to tailor your stay with Crystal just as you like it. Choose from the curated pillow list, select which wines, premium spirits, and soft drinks you would like Crystal to stock your minibar with, take advantage of the shoeshine and packing services, and enjoy gourmet dining in the privacy of your guest room or suite. The turndown service changes the mood from day to night, creating the perfect ambience for when you retire for the night.
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